A weighted U statistic for association analyses considering genetic heterogeneity
نویسندگان
چکیده
منابع مشابه
A weighted U-statistic for genetic association analyses of sequencing data.
With advancements in next-generation sequencing technology, a massive amount of sequencing data is generated, which offers a great opportunity to comprehensively investigate the role of rare variants in the genetic etiology of complex diseases. Nevertheless, the high-dimensional sequencing data poses a great challenge for statistical analysis. The association analyses based on traditional stati...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2016
ISSN: 0277-6715
DOI: 10.1002/sim.6877